964
UNIT 4
Maintenance of the Body
25
Glomerular capillary
covered by podocytes
that form the visceral layer
of glomerular capsule
Glomerular
capillary endothelium
(podocyte covering
and basement
membrane removed)
Proximal
convoluted
tubule
Parietal layer
of glomerular
capsule
Afferent
arteriole
Glomerular
capsular space
Fenestrations
(pores)
Efferent
arteriole
Podocyte
cell body
Foot processes
of podocyte
Filtration slits
Cytoplasmic extensions
of podocytes
(a) Glomerular capillaries and the visceral layer of
the glomerular capsule
Figure 25.10
The filtration membrane.
(a)
The visceral (inner) layer of the glomerular
capsule consists of podocytes that surround the glomerular capillaries. Some podocytes and the
basement membrane have been removed to show the fenestrations (pores) in the underlying
capillary wall.
(b)
Scanning electron micrograph of the visceral layer (6000
3
).
(c)
Diagram of a
section through the filtration membrane showing all three structural elements.
(c) Three layers of the filtration membrane
(b) Filtration slits between the podocyte foot processes
Fenestration
(pore)
Filtrate
in capsular
space
Foot
processes
of podocyte
Filtration
slit
Slit
diaphragm
• Basement membrane
• C
apillary endothelium
C
apillary
Filtration membrane
• F
oot processes of podocyte
of glomerular capsule
Plasma
Foot
processes
Filtration slits
Podocyte
cell body
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