Chapter 17
Blood
643
17
Hematopoietic stem cell
(hemocytoblast)
Myeloid stem cell
Lymphoid stem cell
Myeloblast
Myeloblast
Monoblast
Myeloblast
B lymphocyte
precursor
T lymphocyte
precursor
Stem cells
Committed
cells
Promyelocyte
Promyelocyte
Promyelocyte
Promonocyte
Eosinophilic
myelocyte
Neutrophilic
myelocyte
Basophilic
myelocyte
Eosinophilic
band cells
Neutrophilic
band cells
Basophilic
band cells
Developmental
pathway
Eosinophils
Neutrophils
Basophils
Granular
leukocytes
(a)
(b)
(c)
(d)
(f)
Effector T cells
Monocytes
T lymphocytes
(e)
B lymphocytes
Macrophages (tissues)
Agranular
leukocytes
Some become
Some become
Plasma cells
Some become
Figure 17.11
Leukocyte formation.
Leukocytes arise from ancestral stem cells
called hematopoietic stem cells.
(a–c)
Granular
leukocytes develop via a sequence involving
myeloblasts.
(d)
Monocytes, like granular
leukocytes, are progeny of the myeloid stem
cell and share a common precursor with
neutrophils (not shown).
(e)
Only lymphocytes
arise via the lymphoid stem cell line.
previous page 677 Human Anatomy and Physiology (9th ed ) 2012 read online next page 679 Human Anatomy and Physiology (9th ed ) 2012 read online Home Toggle text on/off